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Recombinant Human SMT3H1, N-6His, E.coli

产品描述

概述

Recombinant Human Small Ubiquitin-Related Modifier 3 is produced by our E.coli expression system and the target gene encoding Met1-Phe103 is expressed with a 6His tag at the N-terminus.

使用说明

This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

TagN-6His
种属Human
表达系统E.coli
Accession#P55854
SourceE.coli
Formulation_DescriptionLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
ReconstitutionDissolve the lyophilized protein in distilled water.
PurityGreater than 95% as determined by reducing SDS-PAGE.
EndotoxinLess than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
BackgroundSUMO3 belongs to the SUMO protein family and operates like ubiquitin. Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polyer. Nevertheless unlike ubiquitin that targets proteins for degration, SUMO3 takes part in several cellular processess, such as nuclear transport, transcription regulation, apoptosis and protein stability. SUMO3 participates in amyloid beta generation and has a key role in the oneset or progression of Alzheimer's disease.
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