产品描述 概述Recombinant Human 40S Ribosomal Protein S19 is produced by our E.coli expression system and the target gene encoding Pro2-His145 is expressed. 使用说明This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. 技术规格Tag | None | 种属 | Human | 表达系统 | E.coli | Accession# | P39019 | Source | E.coli | Formulation_Description | Lyophilized from a 0.2 μm filtered solution of PBS, 1mM EDTA, pH 7.4. | Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. | Reconstitution | Dissolve the lyophilized protein in distilled water. | Purity | Greater than 95% as determined by reducing SDS-PAGE. | Endotoxin | Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test. | Background | 40S Ribosomal Protein S19 (RPS19) is a ribosomal protein that Belongs to the ribosomal protein S19e family. RPS19 is located in the nucleoli, and higher level expression is seen in colon carcinoma tissue than normal colon tissue. It required for pre-rRNA processing and maturation of 40S ribosomal subunits. RPS19 plays a role in many biological processes, such as endocrine pancreas development, erythrocyte differentiation, mRNA metabolic process. Defects in RPS19 are the cause of Diamond-Blackfan anemia type 1 (DBA1), which is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. |
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