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Recombinant Human CTSA, C-6His, Human cells

产品描述

概述

Recombinant Human Cathepsin A is produced by our Mammalian expression system and the target gene encoding Ala29-Tyr480 is expressed with a 6His tag at the C-terminus.

使用说明

This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

TagC-6His
种属Human
表达系统Human cells
Accession#P10619
SourceHuman Cells
Formulation_DescriptionSupplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
StorageStore at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
PurityGreater than 95% as determined by reducing SDS-PAGE.
EndotoxinLess than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
BackgroundCathepsin A is active in cellular compartments called lysosomes. These compartments contain enzymes that digest and recycle materials when they are no longer needed. Cathepsin A interacts with the enzymes β-galactosidase and neuraminidase 1, which play a role in the breakdown of complexes of sugar molecules (oligosaccharides) attached to certain proteins (glycoproteins) or fats (glycolipids). Cathepsin A forms a complex with these two enzymes and directs their transport within the cell to the lysosomes. Within lysosomes, cathepsin A activates the enzymes and prevents their breakdown.
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