产品信息 >> 蛋白相关 >> 重组蛋白;
Recombinant Human Cathepsin D , C-6His, Human cells

产品描述

概述

Recombinant Human Cathepsin D is produced by our Mammalian expression system and the target gene encoding Leu21-Leu412 is expressed with a 6His tag at the C-terminus.

使用说明

This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

TagC-6His
种属Human
表达系统Human cells
Accession#P07339
SourceHuman Cells
Formulation_DescriptionSupplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
StorageStore at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
PurityGreater than 95% as determined by reducing SDS-PAGE.
EndotoxinLess than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
BackgroundThe protein acid protease active in intracellular protein breakdown and involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. It is specificity similar to, but narrower than, that of pepsin A and it does not cleave the 4-Gln-|-His-5 bond in B chain of insulin. It consists of a light chain and a heavy chain and expressed in the aorta extrcellular space. The Val-58 allele is significantly overrepresented in demented patients (11.8%) compared with non-demented controls (4.9%). Carriers of the Val-58 allele have a 3.1-fold increased risk for developing AD than non-carriers.It belongs to the peptidase A1 family
上一篇:Recombinant Human CT
下一篇:Recombinant Mouse CT
关于我们 | 产品信息 | 技术服务 | 联系我们

     电话:400-832-8698    地址:北京怀柔雁栖开发区光织谷东区二号楼 

   备案/许可证编号京ICP备2020036913号