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Recombinant Human Eotaxin-3/CCL26

产品描述

概述

CCL26 is novel CC family chemokine, also known as TARC (thymus and activation regulated chemokine). It is encoded by CCL26 gene, which is located on Chr.7 in humans, and ubiquitously expressed at low levels in various tissues including heart and ovary. CCL26 elicits its effects activity by binding to the cell surface chemokine receptor CCR3, and chemotactic for eosinophils and basophils.

使用说明

This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
Purity> 97 % by SDS-PAGE and HPLC analyses.
SourceEscherichia coli.
Biological ActivityFully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CCR3 transfected HEK293 cells is in a concentration range of 0.5-2.0 μg/ml.
FormulationLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
EndotoxinLess than 1 EU/μg of rHuEotaxin-3/CCL26 as determined by LAL method.
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 C. Further dilutions should be made in appropriate buffered solutions.
AA SequenceTRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L
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