中文名称

甲基苯丙胺单克隆抗体

别    名

d-Desoxyephedrine hydrochloride; d-N;   α-Dimethylphenethylamine hydrochloride; Methylamphetamine hydrochloride;   METH.   

抗体来源

Mouse

克隆类型

Monoclonal

产品应用

ELISA=1:500-1000  
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

分 子 量

0.18569kDa

性    状

Liquid or Solid

浓    度

1mg/ml

免 疫 原

KLH conjugated Methamphetamine: 

亚    型

IgG

纯化方法

affinity purified by Protein G

储 存 液

0.01M TBS(pH7.4) with 1% BSA, 0.03%   Proclin300 and 50% Glycerol.

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated   freeze/thaw cycles.

PubMed

PubMed

产品介绍

Methamphetamine (METH) is closely   related chemically to amphetamine (AMPH). METH is a potent central nervous   system stimulant with additional peripheral sympathomimetic effects. METH and   AMPH have been used clinically in the treatment of obesity, minimal brain   dysfunction, narcolepsy, depression and to counter fatigue. They are also   subjected to widespread abuse. METH is an indirect agonists. It causes the   release of newly synthesized norepinephrine and dopamine and it blocks the re   uptake of these transmitters from the synapse. This can lead to an increase   in the concentration of catecholamines in the synapse as well as an overall   increase in catecholaminergic activity in the brain. The mechanism of METH   induced neurotoxicity for all monoaminergic cell types may lie primarily with   the dopaminergic system in the striatum. It may also lie with the interaction   between METH induced release of dopamine and its ability to inhibit monoamine   oxidase.
 
  SWISS:
  N/A
 
  CAS:
  169565-17-7
 
  Important   Note:
  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications. 
 
  抗甲基安非他明抗体
  过量的使用冰毒可导致急性中毒。严重者出现精神混乱、性欲亢进、焦虑、烦躁、幻觉状态。长期滥用可造成慢性中毒、体重下降、消瘦、溃疡、脓肿、指甲脆化和夜间磨牙。静脉注射方式滥用者可引起各种感染合并症；包括肝炎、细菌性心内膜炎、败血症和艾滋病等。