中文名称

甲硝唑单克隆抗体

别    名

2-Methyl-5-nitroimidazole-1-ethanol  

抗体来源

Mouse

克隆类型

Monoclonal

产品应用

ELISA=1:500-1000  
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

分 子 量

0.17115kDa

性    状

Liquid or Solid

浓    度

1mg/ml

免 疫 原

KLH conjugated with   Metronidazole: 

亚    型

IgG

纯化方法

affinity purified by Protein A

储 存 液

0.01M TBS(pH7.4) with 1% BSA, 0.03%   Proclin300 and 50% Glycerol.

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated   freeze/thaw cycles.

PubMed

PubMed

产品介绍

Metronidazole is a nitroimidazole   antibiotic medication used particularly for anaerobic bacteria and protozoa.   Metronidazole is an antibiotic, amebicide, and antiprotozoal.Metronidazole,   taken up by diffusion, is selectively absorbed by anaerobic bacteria and   sensitive protozoa. Once taken up by anaerobes, it is non-enzymatically   reduced by reacting with reduced ferredoxin, which is generated by pyruvate   oxido-reductase. Many of the reduced nitroso intermediates will form   sulfinamides and thioether linkages with cysteine-bearing enzymes, thereby   deactivating these critical enzymes. As many as 150 separate enzymes are   affected.In addition or alternatively, the metronidazole metabolites are   taken up into bacterial DNA, and form unstable molecules. This function only   occurs when metronidazole is partially reduced, and because this reduction   usually happens only in anaerobic cells, it has relatively little effect upon   human cells or aerobic bacteria.
 
  SWISS:
  N/A
 
  CAS:
  443-48-1
 
  Important   Note:
  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications.