中文名称

比伐卢定（水蛭素类似物）抗体

别    名

Bivalirudin; 128270-60-0  

抗体来源

Rabbit

克隆类型

Polyclonal

产品应用

ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

分 子 量

2.108kDa

细胞定位

分泌型蛋白 

性    状

Liquid or Solid

浓    度

1mg/ml

免 疫 原

KLH conjugated synthetic peptide   Bivalirudin (d-FPRPGGGGNGDFEEIPEEYL): 

亚    型

IgG

纯化方法

affinity purified by Protein A

储 存 液

0.01M TBS(pH7.4) with 1% BSA, 0.03%   Proclin300 and 50% Glycerol.

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated   freeze/thaw cycles.

PubMed

PubMed

产品介绍

Bivalirudin is a specific and   reversible direct thrombin inhibitor (DTI). Chemically, it is a synthetic   congener of the naturally occurring drug hirudin (found in the saliva of the   medicinal leech Hirudo medicinalis). Bivalirudin is a DTI that overcomes many   limitations seen with indirect thrombin inhibitors, such as heparin.   Bivalirudin is a short, synthetic peptide that is potent, highly specific,   and a reversible inhibitor of thrombin. It inhibits both circulating and   clot-bound thrombin, while also inhibiting thrombin-mediated platelet   activation and aggregation. Bivalirudin has a quick onset of action and a   short half-life. It does not bind to plasma proteins (other than thrombin) or   to red blood cells. Therefore, it has a predictable antithrombotic response.   There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced   Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a   binding cofactor such as antithrombin and does not activate platelets. These   characteristics make bivalirudin an ideal alternative to heparin.
 
  SWISS:
  N/A
 
  CAS:
  128270-60-0
 
  Important   Note:
  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications.