中文名称

醋酸阿托西班抗体

别    名

1-(3-Mercaptopropanoic   acid)-2-(O-ethyl-D-tyrosine)-4-L-threonine-8-L-ornithineoxytocin;   1-Deamino-2-D-Tyr-(O-ethyl)-4-Thr-8-ornoxytocin;   (2S)-N-[(1S)-4-Amino-1-(carbamoylmethylcarbamoyl)butyl]-1-[(4S,7S,13S,16R)-13-[(2S)-butan-2-yl]-7-(carbamoylmethyl)-1  

抗体来源

Rabbit

克隆类型

Polyclonal

产品应用

ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

细胞定位

分泌型蛋白 

性    状

Liquid or Solid

浓    度

1mg/1ml

免 疫 原

KLH conjugated Atosiban, Acetate   : 

亚    型

IgG

纯化方法

affinity purified by Protein A

储 存 液

0.01M TBS(pH7.4) with 1% BSA, 0.03%   Proclin300 and 50% Glycerol.

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated   freeze/thaw cycles.

PubMed

PubMed

产品介绍

Atosiban is a nonapeptide,   desamino-oxytocin analogue, and a competitive vasopressin/oxytocin receptor   antagonist (VOTra). Atosiban inhibits the oxytocin-mediated release of   inositol trisphosphate from the myometrial cell membrane. As a result, there   is reduced release of intracellular, stored calcium from the sarcoplasmic   reticulum of myometrial cells, and reduced influx of Ca2+ from the   extracellular space through voltage gated channels. In addition, atosiban   suppresses oxytocin-mediated release of PGE and PGF from the decidua.
 
  SWISS:
 
  CAS:
  90779-69-4
 
  Important   Note:
  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications.