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Rabbit Anti-Vapreotide, Acetate antibody

英文名称

Vapreotide, Acetate

中文名称

醋酸伐普肽抗体

    

103222-11-3  

抗体来源

Rabbit

克隆类型

Polyclonal

产品应用

IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

    

Liquid or Solid

    

1mg/1ml

  

KLH conjugated Vapreotide,   Acetate: 

    

IgG

纯化方法

affinity purified by Protein A

  

0.01M TBS(pH7.4) with 1% BSA, 0.03%   Proclin300 and 50% Glycerol.

保存条件

Shipped at 4. Store at -20 °C for one year. Avoid repeated   freeze/thaw cycles.

PubMed

PubMed

产品介绍

Vapreotide (Sanvar) is a synthetic   somatostatin analog. It is used in the treatment of esophageal variceal   bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea.
 
 
Function:
  Vapreotide attenuates SP-triggered intracellular calcium increases and NF-κB   activation in a dose-dependent manner. Vapreotide also inhibits SP-induced   IL-8 and MCP-1 production in HEK293-NK1R and U373MG cell lines. Vapreotide   inhibits HIV-1 infection of human MDM in vitro, an effect that is reversible   by SP pretreatment. In vivo: Vapreotide decreases portal pressure and blood   flow of collateral circulation in rats with cirrhosis. Vapreotide   administrated via the intravenous route is simple to use, with practically no   contraindications and few, usually minor, side effects.
 
 
SWISS:
 
 
CAS:
  103222-11-3
 
 
Important   Note:
  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications. 

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