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Rabbit Anti-mouse IgM antibody

英文名称

Rabbit Anti-mouse IgM

中文名称

兔抗小鼠IgM

抗体来源

Rabbit

克隆类型

Polyclonal

产品应用

WB=1:1000-5000 ELISA=1:2000-10000 IHC-P=1:200-1000 IHC-F=1:200-1000  
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

  

900kDa

    

Lyophilized or Liquid

    

10mg/1ml

  

IgG:full length 

    

IgG

纯化方法

affinity purified by Protein A

  

0.01M PBS(pH7.4)

保存条件

Storage: Store at –20 oC for one year.   Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room   temperature for at least one month and for greater than a year when kept at   -20oC. When reconstituted in sterile distilled water or diluent supplied,   theantibody is stable for at least two weeks at 2-4 °C.

产品介绍

IgM normally constitutes about 10% of   serum immunoglobulins. IgM antibody is prominent in early immune responses to   most antigens and is largely confined to plasma due to it's large size.   Monomeric IgM is expressed as a membrane bound antibody on the surface of B   cells and as a pentamer when secreted by plasma cells. Due to it's high   valency IgM is more efficient than other isotypes is binding antigens with   repeating epitopes (virus particles and red blood cells) and is more   efficient than IgG in activiating the complement pathway. The gene for the mu   constant region contains four domains separated by short intervening   sequences.
 
  Important Note:
  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications. 

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