首页 | 产品信息 | 技术研发 | 常规服务 | 订单下载 | 访客留言 | 联系我们  
 产品分类 
· 蛋白相关
·重组蛋白;
·蛋白提取试剂盒;
·蛋白定量试剂盒;
·蛋白纯化试剂;
·细胞培养添加蛋白因子;
·蛋白Marker
· 核酸相关
·吸附柱法核酸提取试剂盒;
·磁珠法核酸提取试剂盒
·免核酸提取样品保存液/核酸释放剂;
·核酸采集与保护套装;
·一次性病毒采样管套装;
·一步法新型冠状病毒荧光定量PCR试剂盒
·表达质粒
·一次性核酸胶体金试纸条
· 试剂盒相关
·ELISA 试剂盒;
·细胞凋亡检测试剂盒;
·细胞转染试剂;
·ECL高灵敏度化学发光试剂盒
· 抗体相关
·一抗;
·二抗;
·体外诊断(IVD)活性抗体;
·抗体纯化试剂
· CDMO服务
·细胞株开发;
·细胞培养工艺开发;
·蛋白纯化工艺开发;
·制剂工艺开发;
·中试放大生产;
·GMP生产服务
· 其他
·核酸清除剂
·灭菌注射用水
·荧光染料
 技术研发分类 
· 蛋白定制服务
· 抗体定制服务
· 试剂盒定制服务
· 课题项目服务
 常规服务分类 
· IF及IHC技术服务
· Western blot服务
· 蛋白纯化及标记服务
· 实时荧光定量PCR
产品信息 >> 蛋白相关 >> 重组蛋白;
Recombinant Human UBE2L3

产品描述

概述

Ubiquitin-conjugating enzyme E2 L3 belongs to the ubiquitin-conjugating enzyme family and is encoded by the UBE2L3 gene in humans. The ubiquitin-conjugating enzymes, also known as E2 enzymes and more rarely as ubiquitin-carrier enzymes, take part in the second step in the ubiquitination reaction. In this reaction, E1 activates the ubiquitin by covalently attaching the molecule to its active site cysteine residue. The activated ubiquitin is then transferred to an E2 cysteine and then the E2 molecule binds E3 via a structurally conserved binding region. The UBE2L3 specifically acts with HECT-type and RBR family E3 ubiquitin-proteinshown to interact with UBOX5, ARIH1, Cbl gene, UBE3A and NEDD4. Down-regulated during the S-phase it is involved in progression through the cell cycle. Additionally, UBE2L3 regulates nuclear hormone receptors transcriptional activity and plays a role in myelopoiesis.

使用说明

This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
Purity> 95 % by SDS-PAGE and HPLC analyses.
SourceEscherichia coli.
Biological ActivityData is not available.
FormulationLyophilized from a 0.2 μm filtered concentrated solution in PBS, 1 mM DTT, pH 7.5.
EndotoxinLess than 1 EU/μg of rHuUBE2L3, His as determined by LAL method.
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA SequenceMHHHHHHAMA ASRRLMKELE EIRKCGMKNF RNIQVDEANL LTWQGLIVPD NPPYDKGAFR IEINFPAEYP FKPPKITFKT KIYHPNIDEK GQVCLPVISA ENWKPATKTD QVIQSLIALV NDPQPEHPLR ADLAEEYSKD RKKFCKNAEE FTKKYGEKRP VD
上一篇:Recombinant Human UB    下一篇:Recombinant Human UB
关于我们   |   诚聘英才   |   信息发布   |   新品推荐   |   技术支持

     电话:400-832-8698    地址:北京怀柔雁栖开发区光织谷东区二号楼 

   备案/许可证编号京ICP备2020036913号

京ICP备2020036913号    技术支持:华大网络