首页 | 产品信息 | 技术研发 | 常规服务 | 订单下载 | 访客留言 | 联系我们  
 产品分类 
· 蛋白相关
·重组蛋白;
·蛋白提取试剂盒;
·蛋白定量试剂盒;
·蛋白纯化试剂;
·细胞培养添加蛋白因子;
·蛋白Marker
· 核酸相关
·吸附柱法核酸提取试剂盒;
·磁珠法核酸提取试剂盒
·免核酸提取样品保存液/核酸释放剂;
·核酸采集与保护套装;
·一次性病毒采样管套装;
·一步法新型冠状病毒荧光定量PCR试剂盒
·表达质粒
·一次性核酸胶体金试纸条
· 试剂盒相关
·ELISA 试剂盒;
·细胞凋亡检测试剂盒;
·细胞转染试剂;
·ECL高灵敏度化学发光试剂盒
· 抗体相关
·一抗;
·二抗;
·体外诊断(IVD)活性抗体;
·抗体纯化试剂
· CDMO服务
·细胞株开发;
·细胞培养工艺开发;
·蛋白纯化工艺开发;
·制剂工艺开发;
·中试放大生产;
·GMP生产服务
· 其他
·核酸清除剂
·灭菌注射用水
·荧光染料
 技术研发分类 
· 蛋白定制服务
· 抗体定制服务
· 试剂盒定制服务
· 课题项目服务
 常规服务分类 
· IF及IHC技术服务
· Western blot服务
· 蛋白纯化及标记服务
· 实时荧光定量PCR
产品信息 >> 蛋白相关 >> 重组蛋白;
Recombinant Murine IL-10

产品描述

概述

Interleukin-10 (IL-10) is encoded by the IL10 gene and expressed in monocytes and Type 2 T helper cells (Th2). The biological activities of IL-10 are mediated by the IL-10 receptor complex, which is composed of the ligand-binding IL-10 Rα/R1 and the accessory IL-10 Rβ/R2 subunits. IL-10 is capable of inhibiting the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by T helper cells. IL-10 is classified as a class 2 cytokine which consist of IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26, several interferons and interferon-like molecules. Mature murine IL-10 shares 70 %-77 % amino acid sequence identity with human, bovine, porcine IL-10, but murine IL-10 does not act on human cells.

使用说明

This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
Purity> 97 % by SDS-PAGE and HPLC analyses.
SourceEscherichia coli.
Biological ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine MC/9-2 cells is less than 1 ng/ml, corresponding to a specific activity of > 1.0 × 106 IU/mg.
FormulationLyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
EndotoxinLess than 1 EU/μg of rMuIL-10 as determined by LAL method.
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10 mM HCl to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA SequenceSRGQYSREDN NCTHFPVGQS HMLLELRTAF SQVKTFFQTK DQLDNILLTD SLMQDFKGYL GCQALSEMIQ FYLVEVMPQA EKHGPEIKEH LNSLGEKLKT LRMRLRRCHR FLPCENKSKA VEQVKSDFNK LQDQGVYKAM NEFDIFINCI EAYMMIKMKS


上一篇:Recombinant Human CN    下一篇:Recombinant Murine T
关于我们   |   诚聘英才   |   信息发布   |   新品推荐   |   技术支持

     电话:400-832-8698    地址:北京怀柔雁栖开发区光织谷东区二号楼 

   备案/许可证编号京ICP备2020036913号

京ICP备2020036913号    技术支持:华大网络