中文名称

血小板活化因子抗体

别    名

platelet-activating factor;   1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine;   1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine monohydrate;   2-Acetyl-1-hexadecyl-sn-glycero-3-phosphocholine; 3-sn-Phosphatidylcholine;   1-hexadecyl-2-acetyl, PAF(C16.  

抗体来源

Rabbit

克隆类型

Polyclonal

交叉反应

Rat

产品应用

ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

分 子 量

0.524kDa

性    状

Liquid or Solid

浓    度

1mg/ml

免 疫 原

KLH conjugated PAF

亚    型

IgG

纯化方法

affinity purified by Protein A

储 存 液

0.01M TBS(pH7.4) with 1% BSA, 0.03%   Proclin300 and 50% Glycerol.

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated   freeze/thaw cycles.

PubMed

PubMed

产品介绍

Platelet-activating factor, a compound   that reduces inflammation by increasing permeability of blood vessels and   contracting various involuntary muscles such as those in airways. It is a   phospholipid with a wide range of proinflammatory actions, is immediately   degraded and inactivated in vivo by PAF acetylhydrolase.
 
  SWISS:
  N/A
 
  CAS:
  74389-68-7
 
  Important   Note:
  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications. 
 
  血小板活化因子（platelet-activating factor，PAF）是一种内源性具有生物活性的磷脂。由中性粒细胞、血小板、肥大细胞、内皮细胞和巨噬细胞产生。除早期发现它有强烈引起血小板聚集和脱颗粒作用外，近年来的研究发现它还具有广泛的生物活性，作为一种独特的细胞因子参与体内多种生理、病理过程，包括激活中性粒细胞，使其聚集、趋化、释放氧自由基和白三烯，抑制T细胞增殖，刺激B细胞合成IgG和IgE，抑制心肌收缩力，增加血管通透性，引起体循环血压下降和肺动脉高压等。由于它具有广泛的高强度的生物活性，故PAF被认为是与过敏反应有关的关键性介质之一。