中文名称

5甲基胞嘧啶抗体

别    名

5-Methyl Cytidine; 5 m C; 5 mC; 5 me   C; 5 Me Cytidine; 5 MeCyd; 5 Methyl Cytidine; 5 MethylCytosine; 5-mC; 5-Me   Cytidine; 5-Methyl-Cytosine; 5-MethylCytidine.  

抗体来源

Rabbit

克隆类型

Polyclonal

交叉反应

Human, 

产品应用

ELISA=1:500-1000 Flow-Cyt=1ug/Test  
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

细胞定位

细胞核 

性    状

Liquid or Solid

浓    度

1mg/ml

免 疫 原

KLH conjugated 5 MethylCytosine: 

亚    型

IgG

纯化方法

affinity purified by Protein A

储 存 液

0.01M TBS(pH7.4) with 1% BSA, 0.03%   Proclin300 and 50% Glycerol.

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated   freeze/thaw cycles.

PubMed

PubMed

产品介绍

Cytidine is a nucleoside formed by a   cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is   methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine   (5-mC), a potent epigenetics marker and regulator of gene expression. The   reverse reaction (cytidine demethylation) starts with its oxidation to   hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine.   Several enzymes, including the Tet family of proteins have been implicated in   cytidine demethylation.
 
  Subcellular   Location:
  Nuclear.
 
  SWISS:
  N/A
 
  CAS:
  58366-64-6
 
  Important   Note:
  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications.