中文名称

甲状腺素T4抗体

别    名

Thyroxine 4; T4; Tg4; L-Thyroxine;   Thyroxine; 3,3′,5,5″-Tetraiodo-L-thyronine,   3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine.  

抗体来源

Rabbit

克隆类型

Polyclonal

交叉反应

(predicted: Human, )

产品应用

ELISA=1:500-1000  
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

分 子 量

0.77687kDa

细胞定位

分泌型蛋白 

性    状

Liquid

浓    度

1mg/ml

免 疫 原

KLH conjugated synthetic peptide   derived from human T4/L-Thyroxine: 

亚    型

IgG

纯化方法

affinity purified by Protein A

储 存 液

0.01M TBS(pH7.4) with 1% BSA, 0.03%   Proclin300 and 50% Glycerol.

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw   cycles.

PubMed

PubMed

产品介绍

Hormone produced by the thyroid glands   to regulate metabolism by controlling the rate of oxidation in cells. Cases   of hypothyroidism, where the gland is insufficiently active, can be treated   by administration of thyroxine or a combination of thyroxine and triiodothyronine.   L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones   produced from thyroglobulin in the thyroid follicular cells. The stimulation   of metabolic rate and regulation of growth and development by these hormones   appear to be due to their effects on DNA transcription and, thus, protein   synthesis.
 
  Subcellular   Location:
  Secreted
 
  SWISS:
  N/A
 
  Gene ID:
  51-48-9
 
  Important   Note:
  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications. 
 
  甲状腺素（Thyroxine, T4）是甲状腺分泌最多的一种激素，血液中的T4全部由甲状腺分泌而来，故血液中T4的浓度能很好地反应甲状腺功能状态。正常情况下，血液中60%的T4与甲状腺素结合球蛋白（TBG）结合，30%与甲状腺素结合前蛋白（TBPA）结合，其余约10%与白蛋白结合，仅约0.03-0.04%呈游离状态。由于T4与TBG亲合力较高，所以血中T4的水平最易受到TBG的影响。