中文名称

甘丙肽受体拮抗剂抗体

别    名

Galanin receptor antagonist;   Reversible galanin receptor antagonist; M15.  

抗体来源

Rabbit

克隆类型

Polyclonal

交叉反应

(predicted: Human, )

产品应用

ELISA=1:500-1000  
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

分 子 量

2kDa

细胞定位

分泌型蛋白 

性    状

Liquid

浓    度

1mg/ml

免 疫 原

KLH conjugated synthetic peptide of   Galantide:1-20/20 

亚    型

IgG

纯化方法

affinity purified by Protein A

储 存 液

0.01M TBS(pH7.4) with 1% BSA, 0.03%   Proclin300 and 50% Glycerol.

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated   freeze/thaw cycles.

PubMed

PubMed

产品介绍

The galanin antagonist Galantide, a   chimeric peptide obtained from amino acids 1-13 of galanin attached to the C   terminal fragment of bradykinin, has been found to improve social memory in   `social recognition' tests when i.c.v. administered at doses varying from   6-6000 nmoles. Galantide causes widespread antagonism to the action of   galanin and reversibly blocks the neuronal actions of galanin in a dose   dependent manner. It inhibits the release of acetylcholine, reduces the   response to galanin in the hypothalamus, and blocks the effect of galanin on   glucose induced insulin secretion. 
 
  Subcellular   Location:
  Secreted.
 
  Database   links:
 
  Important   Note:

  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications.