中文名称

γ氨基丁酸抗体

别    名

gamma-aminobutyric acid; gamma   aminobutyric acid; 4 aminobutanoic acid; Gamma amino butyric acid; γ－aminobutyric acid (GABA).  

抗体来源

Rabbit

克隆类型

Polyclonal

交叉反应

Rat, 

产品应用

ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 （石蜡切片需做抗原修复） 
  not yet tested in other applications.
  optimal dilutions/concentrations should be determined by the end user.

细胞定位

细胞浆 细胞膜 分泌型蛋白 

性    状

Liquid or Solid

浓    度

1mg/ml

免 疫 原

KLH conjugated GABA: 

亚    型

IgG

纯化方法

affinity purified by Protein A

储 存 液

0.01M TBS(pH7.4) with 1% BSA, 0.03%   Proclin300 and 50% Glycerol.

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated   freeze/thaw cycles.

PubMed

PubMed

产品介绍

Gamma-aminobutyric acid (GABA) is a   major inhibitory neurotransmitter. GABA acts at inhibitory synapses in the   brain and spinal cord. Inhibition is provoked by GABA binding resulting in   hyperpolarization of the synaptic transmembrane potential of the affected neuron.   GABA binding causes ion channels to open allowing either the flow of chloride   or potassium ions into or out of the cell.
 
  SWISS:
  N/A
 
  CAS:
  56-12-2
 
  Important Note:
  This product as supplied is intended for research use only, not for use in   human, therapeutic or diagnostic applications. 
 
  γ-氨基丁酸（简称GABA）是一种天然存在的非蛋白质氨基酸，是哺乳动物中枢神经系统中重要的抑制性神经传达物质，约50%的中枢神经突触部位以GABA为递质。在人体大脑皮质、海马、丘脑、基底神经节和小脑中起重要作用，并对机体的多种功能具有调节作用。当人体内GABA缺乏时，会产生焦虑、不安、疲倦、忧虑等情绪，一般长久处于高压力族群如身处竞争环境中的人群、运动员、上班族等，都很容易缺乏GABA需要及时补充以便舒缓情绪。