Biotinylated Recombinant Human Leukocyte Surface Antigen CD47 is produced by our Mammalian expression system and the target gene encoding Gln19-Pro139 is expressed with a Fc, Avi tag at the C-terminus.
This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
|Formulation_Description||Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.|
|Storage||Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.|
|Reconstitution||Dissolve the lyophilized protein in distilled water.|
|Purity||Greater than 95% as determined by reducing SDS-PAGE.|
|Endotoxin||Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.|
|Background||CD47(Integrin-Associated Protein,IAP) is a 40 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.|