产品描述 概述Recombinant Human Sentrin-specific Protease 2 is produced by our E.coli expression system and the target gene encoding Asp363-Leu589 is expressed. 使用说明This material is offered by Novin Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. 技术规格| Tag | N-6His, SUMO | | 种属 | Human | | 表达系统 | E.coli | | Accession# | Q9HC62 | | Source | E.coli | | Formulation_Description | Supplied as a 0.2 μm filtered solution of 50mM HEPES, 5% Glycerol, pH 7.4. | | Storage | Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles. | | Purity | Greater than 95% as determined by reducing SDS-PAGE. | | Endotoxin | Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test. | | Background | SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. |
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